Aceclofenac-Soluplus&reg Nanocomposites for Increased Bioavailability
نویسندگان
چکیده
منابع مشابه
Pharmacokinetics Study of Aceclofenac in Pakistani Population and Effects of Sucralfate Co-administration on Bioavailability of Aceclofenac
Objective: Aceclofenac is a phenylacetic acid derivative; this nonsteroidal anti-inflammatory drug is a potent anti-inflammatory analgesic and antipyretic. The objectives of this study were to conduct a pharmacokinetic study of aceclofenac in a Pakistani population, to compare the pharmacokinetic profile of the local population with the United Kingdom (UK) and to determine the effect of sucralf...
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The aim of the present work was to tackle the solubility issue of a biopharmaceutics classification system (BCS)-II drug, aceclofenac. Although a number of attempts to increase the aqueous solubility have been made, none of the methods were taken up for scale-up. Hence size reduction technique by a top-down approach using wet milling process was utilized to improve the solubility and, consequen...
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Aceclofenac (AC) is an effective non-steroidal antiinflammatory drug, which possesses remarkable antiinflammatory, analgesic and antipyretic properties. The analgesic and anti-inflammatory efficacy of AC is generally equivalent to that of comparator nonsteroidal antiinflammatory drugs (NSAIDs) with similar onset of action. AC also shows stimulatory effects on glycosaminoglycan synthesis in huma...
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ژورنال
عنوان ژورنال: Soft Nanoscience Letters
سال: 2015
ISSN: 2160-0600,2160-0740
DOI: 10.4236/snl.2015.52003